<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Template Model Builder on Øystein Sørensen</title><link>https://osorensen.no/tags/template-model-builder/</link><description>Recent content in Template Model Builder on Øystein Sørensen</description><generator>Hugo</generator><language>en</language><lastBuildDate>Sat, 14 Mar 2026 00:00:00 +0000</lastBuildDate><atom:link href="https://osorensen.no/tags/template-model-builder/index.xml" rel="self" type="application/rss+xml"/><item><title>A Semiparametric Nonlinear Mixed Effects Model with Penalized Splines Using Automatic Differentiation</title><link>https://osorensen.no/papers/paper15/</link><pubDate>Sat, 14 Mar 2026 00:00:00 +0000</pubDate><guid>https://osorensen.no/papers/paper15/</guid><description>We present an estimation procedure for nonlinear mixed-effects models in which the population trajectory is represented by penalized splines and adapted to individuals via subject-specific transformation parameters. By exploiting the mixed model representation of penalized splines, the level of smoothness can be estimated jointly with other variance components. The approach is illustrated through a case study on infant height growth. arXiv preprint.</description></item></channel></rss>